Article
Parkinson's disease, proteins, and prions: milestones.
Movement disorders : official journal of the Movement Disorder Society - 1 May 2011
Olanow C Warren, McNaught K
Abstract excerpt
Parkinson's disease (PD) is characterized by protein accumulation in the form of Lewy bodies and neurites. It is thus reasonable to consider that alterations in protein handling in the form of increased production, impaired clearance, or both might be central to the etiopathogenesis of the disease. Increasing genetic, laboratory and pathologic evidence has accumulated over the past 25 years supporting this...
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