Article
Two-marker association tests yield new disease associations for coronary artery disease and hypertension.
Human genetics - 1 Dec 2011
Slavin Thomas P, Feng Tao, Schnell Audrey, Zhu Xiaofeng, Elston Robert C
Abstract excerpt
It has been postulated that multiple-marker methods may have added ability, over single-marker methods, to detect genetic variants associated with disease. The Wellcome Trust Case Control Consortium (WTCCC) provided the first successful large genome-wide association studies (GWAS) which included single-marker association analyses for seven common complex diseases. Of those signals detected, only one was...
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