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Article

Nrf2-dependent gene expression is affected by the proatherogenic apoE4 genotype-studies in targeted gene replacement mice.

Journal of molecular medicine (Berlin, Germany) - 1 Oct 2011

Graeser Anne-Christin, Boesch-Saadatmandi Christine, Lippmann Jana, Wagner Anika E, Huebbe Patricia, Storm Niels, Höppner Wolfgang, Wiswedel Ingrid, Gardemann Andreas, Minihane Anne M, Döring Frank, Rimbach Gerald

Abstract excerpt

An apoE4 genotype is an important risk factor for cardiovascular and other chronic diseases. The higher cardiovascular disease risk of apoE4 carriers as compared to the apoE3 genotype has been mainly attributed to the differences in blood lipids between the two genotype subgroups. Recently, a potential protective role of the transcription factor Nrf2 in cardiovascular disease prevention has been suggested. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21626108
DOI: 10.1007/s00109-011-0771-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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