Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of manipulation of the caspase system on myofibrillar protein degradation in vitro.

Journal of animal science - 1 Oct 2011

Kemp C M, Wheeler T L

Abstract excerpt

Apoptosis via the intrinsic caspase 9 pathway can be induced by oxidative stressors hydrogen peroxide (H₂O₂) and N-(4 hydroxyphenol) rentinamide (fenretinide), a synthetic retinoid. Accelerated muscle atrophy and proteolysis in muscle-wasting conditions have been linked to oxidative stress and activated protease systems. Therefore, the hypothesis of this study was that proteolysis of myofibrillar proteins could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caspases
Share to SDS gene
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Myofibrils

Share to Protein Denaturation

Source

Identifiers

PMID: 21622882
DOI: 10.2527/jas.2010-3552

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of manipulation of the caspase system on myofibrillar protein degradation in vitro.PMID 21622882Read ↗

The caspase proteolytic system in callipyge and normal lambs in longissimus, semimembranosus, and infraspinatus muscles during postmortem storage.Semantic proximity Read ↗

Cleavage of caspase-12 at Asp94, mediated by endoplasmic reticulum stress (ERS), contributes to stretch-induced apoptosis of myoblasts.Semantic proximity Read ↗

Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis.Semantic proximity Read ↗

Apoptosis of myofibres and satellite cells: exercise‐induced damage in skeletal muscle of the mouseSemantic proximity Read ↗

The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophySemantic proximity Read ↗

Caspase 3 activity is required for skeletal muscle differentiation.Semantic proximity Read ↗

Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity.Semantic proximity Read ↗

DNA‐fragmentation and expression of apoptosis‐related proteins in muscular dystrophiesSemantic proximity Read ↗

Apoptosis of tail muscle during amphibian metamorphosis involves a caspase 9-dependent mechanism.Semantic proximity Read ↗

Evidence for a pro-apoptotic phenotype in skeletal muscle of hypertensive rats.Semantic proximity Read ↗

Apoptotic features accompany acute quadriplegic myopathySemantic proximity Read ↗

Delay of muscle degeneration and necrosis in mdx mice by calpain inhibitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.