Article
Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis.
Journal of muscle research and cell motility - 1 Jan 2007
Honda A, Abe S, Hiroki E, Honda H, Iwanuma O, Yanagisawa N, Ide Y
Abstract excerpt
The mdx mouse, a model of muscular dystrophy, lacks dystrophin, a cell membrane protein. It is known that the lack of dystrophin causes muscle fiber necrosis from 2 weeks after birth, and the majority of necrotic muscle fibers are replaced by regenerated muscle fibers by 4 weeks after birth. A recent study indicated the possibility that mitochondria-mediated intracellular stress, a phenomenon similar to...
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