Article
B7-H3 is associated with the armored-cold phenotype and predicts poor immune checkpoint blockade response in melanoma.
Pathology, research and practice - 1 Apr 2024
Shen Bozhi, Mei Jie, Xu Rui, Cai Yun, Wan Mengyun, Zhou Ji, Ding Junli, Zhu Yichao
Abstract excerpt
Melanoma is the most suitable tumor type for immunotherapy, but not all melanoma patients could respond to immunotherapy. B7 homolog 3 (B7-H3) belongs to the B7 family and is overexpressed in a number of malignant tumors, but the expression pattern of B7-H3 in melanoma has not been well summarized. The expression of B7-H3 was investigated in melanoma and its correlations with features of the tumor...
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