Diversity and plasticity of mononuclear phagocytes

Abstract excerpt

Phagocytes are the founding pillars of innate immunity 1 and, as such, have been the object of intense scrutiny in the past few years. Mononuclear phagocytes constitute a system characterised by considerable diversity. Indeed, two major themes have emerged in recent macrophage investigations: their heterogeneity in different tissue environments and phenotypic plasticity in various physiologic and pathologic...

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