Article
Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.
Investigative ophthalmology & visual science - 1 Dec 2009
Puk Oliver, Dalke Claudia, Calzada-Wack Julia, Ahmad Nafees, Klaften Matthias, Wagner Sibylle, de Angelis Martin Hrabé, Graw Jochen
Abstract excerpt
PURPOSE: The purpose of this study was the morphologic and genetic characterization of the novel eye size mutant Aca23 in the mouse. METHODS: The eyes of the mutants were characterized in vivo by optical low-coherence interferometry, Scheimpflug imaging, and funduscopy. Visual acuity was examined using a virtual optomotor system. Morphology was studied by histology, in situ hybridization, and...
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