Article
Polymorphisms of DNA repair genes XPD and XRCC1 and risk of cataract development.
Experimental eye research - 1 Sept 2007
Unal Mustafa, Güven Mehmet, Batar Bahadir, Ozaydin Ahmet, Sarici Ahmet, Devranoğlu Kazim
Abstract excerpt
The association between oxidative or ultraviolet (UV) light induced DNA damage in the lens epithelium and the development of lens opacities, and the existence of DNA repair in lens epithelial cells have been reported. Polymorphisms of DNA repair enzymes may affect repair efficiency. In this study, we aimed to determine the frequency of polymorphisms in two DNA repair enzyme genes, xeroderma pigmentosum...
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