Article
Relationship between RANTES polymorphisms and respiratory syncytial virus bronchiolitis in a Japanese infant population.
Japanese journal of infectious diseases - 1 Jan 2011
Hattori Satoshi, Shimojo Naoki, Mashimo Toichi, Inoue Yuzaburo, Ono Yasuhiko, Kohno Yoichi, Okamoto Yoshitaka, Hata Akira, Suzuki Yoichi
Abstract excerpt
Respiratory syncytial virus (RSV) is the most important virus associated with bronchiolitis in infants and young children. The regulated upon activation, normal T-cell expressed and secreted protein (RANTES, also known as CCL5) appears to be a key player in the etiology of RSV-infected airway inflammation. In this study, we genotyped three single-nucleotide polymorphisms in the RANTES gene: -403G/A, -28C/G, and...
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