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Article

The lin-4 gene controls fat accumulation and longevity in Caenorhabditis elegans.

International journal of molecular sciences - 1 Jan 2010

Zhu Chun, Ji Chen-Bo, Zhang Chun-Mei, Gao Chun-Lin, Zhu Jin-Gai, Qin Da-Ni, Kou Chun-Zhao, Zhu Guan-Zhong, Shi Chun-Mei, Guo Xi-Rong

Abstract excerpt

Previous studies have determined that lin-4, which was the first miRNA to be discovered, controls the timing of cell fate determination and life span in Caenorhabditis elegans. However, the mechanism of lin-4 involvement in these processes remains poorly understood. Fat storage is an essential aspect of the life cycle of organisms, and the function of lin-4 in fat accumulation is not clear. In this study, we...

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PMID: 21614175
DOI: 10.3390/ijms11124814
PMCID: PMC3100830

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OGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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