Article
[Molecular targeted therapy and genomic evolution of breast cancer].
Nihon rinsho. Japanese journal of clinical medicine - 1 Aug 2015
Sato Fumiaki, Toi Masakazu
Abstract excerpt
Owing to development of next generation sequencer (NGS), deep biological insights of breast cancer have been provided. Information of genomic mutations and rearrangements in patients' tumors is required to understand the mechanism in resistance of molecular targeted medicine. To date, NGS analyses illustrated not only base substitution patterns and lists of driver mutations and key rearrangements, but also a...
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