Article
cAMP stimulation of Dictyostelium discoideum destabilizes the mRNA for 117 antigen.
The Journal of biological chemistry - 5 Jun 1990
Juliani M H, Souza G M, Klein C
Abstract excerpt
Transcription of the 117 gene and changes in its mRNA levels in Dictyostelium discoideum were studied by mRNA hybridization with a cDNA probe. In wild type cells (Ax-2), the expression is developmentally regulated during cell aggregation, while in the aggregateless mutant, Agip 45, 117 mRNA is no...
Topics
- Adenylyl Cyclase Inhibitors
- Bucladesine
- Caffeine
- Cyclic AMP
- DNA Probes
- Dictyostelium
- Down-Regulation
- Enzyme Activation
- Gene Expression Regulation
- Mutation
- Nucleic Acid Hybridization
- Protein Biosynthesis
- Protein Kinases
- RNA, Messenger
- Transcription, Genetic