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Article

IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2011

Silver Jonathan S, Stumhofer Jason S, Passos Sara, Ernst Matthias, Hunter Christopher A

Abstract excerpt

IL-6 and IL-27 are closely related cytokines that play critical but distinct roles during infection with Toxoplasma gondii. Thus, IL-6 is required for the development of protective immunity to this pathogen, whereas IL-27 is required to limit infection-induced pathology. Paradoxically, these factors both signal through gp130, but little is known about how the signals downstream of gp130 are integrated to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21606248
DOI: 10.4049/jimmunol.1004144
PMCID: PMC3119722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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