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Article

Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related cataract development in Han Chinese.

Current eye research - 1 Jul 2011

Luo Yong-Feng, Wang Bin-Bin, Zhou Zhou, Ding Xu-Chen, Hu Shan-Shan, Zhou Guang-Kai, Ma Xu, Qi Yan-Hua

Abstract excerpt

PURPOSE: Epidemiological evidence suggests that ultraviolet (UV) irradiation and oxidative stress play an important role in age-related cataract pathogenesis. UV irradiation and oxidative stress can produce a wide range of DNA damage. Polymorphisms of DNA repair enzymes may affect repair efficiency and the role of DNA repair mechanisms has received attention recently in age-related cataract pathogenesis. In this...

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Source

Identifiers

PMID: 21599457
DOI: 10.3109/02713683.2011.571358

Genes

XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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