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Article

Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration.

Investigative ophthalmology & visual science - 1 Sept 2010

Görgün Ebru, Güven Mehmet, Unal Mustafa, Batar Bahadir, Güven Gülgün S, Yenerel Melda, Tatlipinar Sinan, Seven Mehmet, Yüksel Adnan

Abstract excerpt

PURPOSE: Oxidative stress seems to be an important factor in the development of age-related macular degeneration (AMD). The role of DNA repair mechanisms has also received attention recently in AMD pathogenesis. This case-control study was conducted to determine the frequency of polymorphisms in...

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Source

Identifiers

PMID: 20375340
DOI: 10.1167/iovs.09-4842

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20375340-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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