Article
[Role of the genetic polymorphism of p53 (codon 72) gene in colorectal cancer].
Arquivos de gastroenterologia - 1 Jan 2000
Lima Jacqueline Miranda de, Serafim Patrícia Valéria Pereira, Silva Ismael Dale Cotrim Guerreiro da, Forones Nora Manoukian
Abstract excerpt
BACKGROUND: Polymorphisms are genetic variations that can occur in sequences of codons, leading to defective proteins. p53 is the most commonly gene affected in human cancer. The polymorphism of this gene occurs by a substitution of a base in codon 72 and may increase the risk of cancer. AIM: To...
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