Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro methods for CFTR biogenesis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Matsumura Yoshihiro, Rooney LeeAnn, Skach William R

Abstract excerpt

Cell-free expression systems provide unique tools for understanding CFTR biogenesis because they reconstitute the cellular folding environment and are readily amenable to biochemical and pharmacological manipulation. The most common system for this purpose is rabbit reticulocyte lysate (RRL), supplemented with either canine pancreatic microsomes or semi-permeabilized cells, which has yielded important insights...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cell Extracts
Share to Cell-Free System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Eukaryotic Initiation Factor-2

Share to Intracellular Membranes

Share to Microsomes

Share to Reticulocytes

Share to RNA Caps

Source

Identifiers

PMID: 21594789
DOI: 10.1007/978-1-61779-117-8_16

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro methods for CFTR biogenesis.PMID 21594789Read ↗

CFTR folding and maturation in cells.Semantic proximity Read ↗

Biosynthesis and degradation of CFTR.Semantic proximity Read ↗

CFTR mRNA expression is regulated by an upstream open reading frame and RNA secondary structure in its 5' untranslated region.Semantic proximity Read ↗

Disrupted post-transcriptional regulation of the cystic fibrosis transmembrane conductance regulator (CFTR) by a 5'UTR mutation is associated with a CFTR-related disease.Semantic proximity Read ↗

Activation of the unfolded protein response by deltaF508 CFTR.Semantic proximity Read ↗

Slowing ribosome velocity restores folding and function of mutant CFTR.Semantic proximity Read ↗

C-terminal Truncations Destabilize the Cystic Fibrosis Transmembrane Conductance Regulator without Impairing Its BiogenesisSemantic proximity Read ↗

Comparative processing and function of human and ferret cystic fibrosis transmembrane conductance regulator.Semantic proximity Read ↗

Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein.Semantic proximity Read ↗

The role of regulated CFTR trafficking in epithelial secretionSemantic proximity Read ↗

Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells.Semantic proximity Read ↗

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.