Biosynthesis and degradation of CFTR.

doi:10.1152/physrev.1999.79.1.S167

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Article

Biosynthesis and degradation of CFTR.

Physiological reviews - 1 Jan 1999

Kopito R R

Abstract excerpt

Biosynthesis and Degradation of CFTR. Physiol. Rev. 79, Suppl.: S167-S173, 1999. - Many of the mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that cause cystic fibrosis interfere with the folding and biosynthetic processing of nascent CFTR molecules in the endopl...

Topics

Animals
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Endopeptidases
Endoplasmic Reticulum, Rough
Humans
Molecular Chaperones
Mutation
Protein Folding
Protein Precursors
Ubiquitins

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