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Article

HLA-DQ genotyping combined with serological markers for the diagnosis of celiac disease: is intestinal biopsy still mandatory?

Journal of pediatric gastroenterology and nutrition - 1 Jun 2011

Clouzeau-Girard Haude, Rebouissoux Laurent, Taupin Jean-Luc, Le Bail Brigitte, Kalach Nicolas, Michaud Laurent, Dabadie Alain, Olives Jean-Pierre, Blanco Patrick, Morali Alain, Moreau Jean-François, Lamireau Thierry

Abstract excerpt

OBJECTIVES: The aim of this study was to evaluate the value of HLA-DQ2/DQ8 allelic genotyping combined with serologic testing for the diagnosis of celiac disease (CD). PATIENTS AND METHODS: One hundred seventy children, who underwent jejunal biopsy for digestive symptoms or malnutrition, were tested for HLA-DQ2/DQ8 and serologic markers (tTG and/or anti-endomysial antibodies). Children were classified in 2...

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PMID: 21593645
DOI: 10.1097/MPG.0b013e31820a724d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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