Article
An update on celiac disease histopathology and the road ahead.
Archives of pathology & laboratory medicine - 1 Jul 2012
Bao Fei, Green Peter H R, Bhagat Govind
Abstract excerpt
CONTEXT: Celiac disease (CD) is a common immune-mediated disorder that occurs in genetically predisposed individuals (carriers of HLA-DQ2 and DQ8 haplotypes) on consumption of wheat (gluten). It is characterized by inflammation of the small-intestinal mucosa and myriad gastrointestinal and systemic manifestations. Celiac disease is common in the general population (prevalence, 0.5%-1%). Currently, small-bowel...
Topics
- Atrophy
- Celiac Disease
- Genetic Predisposition to Disease
- Humans
- Inflammation
- Intestinal Mucosa
- Intestine, Small