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Article

Arginine transport through system y(+)L in cultured human fibroblasts: normal phenotype of cells from LPI subjects.

American journal of physiology. Cell physiology - 1 Dec 2000

Dall'Asta V, Bussolati O, Sala R, Rotoli B M, Sebastio G, Sperandeo M P, Andria G, Gazzola G C

Abstract excerpt

In lysinuric protein intolerance (LPI), impaired transport of cationic amino acids in kidney and intestine is due to mutations of the SLC7A7 gene. To assess the functional consequences of the LPI defect in nonepithelial cells, we have characterized cationic amino acid (CAA) transport in human fibroblasts obtained from LPI patients and a normal subject. In both cell types the bidirectional fluxes of arginine are...

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Identifiers

PMID: 11078698
DOI: 10.1152/ajpcell.2000.279.6.C1829

Genes

LAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Arginine transport through system y(+)L in cultured human fibroblasts: normal phenotype of cells from LPI subjects.PMID 11078698Read ↗

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