Article
[Effects of PTEN gene on invasion and migration of ovarian cancer cell line A2780 and related mechanisms].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Mar 2011
Wu Hui-juan, Hao Quan, Wang Ke, Liu Wen-xin, Ma Ding
Abstract excerpt
OBJECTIVE: To evaluate the effects of PTEN on invasive and migration ability of human ovarian cancer cell line A2780 and related mechanisms. METHODS: The plasmid including WT-PTEN and mutant PTEN were transferred into A2780 cells. The invasive and migration ability were measured before and after transfection by transwell chamber and wound-healing assays. The expression of PTEN protein and related proteins in the...
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