Article
[Expression of phosphatase and tensin homology deleted on chromosome ten(PTEN) and p53 protein and their significance in human hepatocellular carcinomas].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jan 2003
Cheng Li-Ming, Wang Si-Yuan, Lin Ju-Sheng
Abstract excerpt
BACKGROUND & OBJECTIVE: Tumor suppressor gene phosphatase and tensin homology deleted on chromosome ten (PTEN) was first reported in 1997 and has become a hot spot shortly after discovery. Mutations of PTEN gene in human hepatocellular carcinomas (HCCs) have been examined by several groups abroad, while little is known about expression of PTEN in HCCs. It has been believed that p53 mutation plays a role in the...
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