Article
Mold-sensitivity in children with moderate-severe asthma is associated with HLA-DR and HLA-DQ.
Allergy - 1 Nov 2010
Knutsen A P, Vijay H M, Kumar V, Kariuki B, Santiago L A, Graff R, Wofford J D, Shah M R
Abstract excerpt
BACKGROUND: Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In this study, we examined T cell responses and HLA class II alleles in children with moderate-severe asthma. METHODS: Ninety-six children with moderate-severe asthma were compared to 90 children with mild asthma. HLA class II genotyping was performed to...
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