HLA and environmental interactions in sarcoidosis.

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Article

HLA and environmental interactions in sarcoidosis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Dec 2008

Rossman M D, Thompson B, Frederick M, Iannuzzi M C, Rybicki B A, Pandey J P, Newman L S, Rose C, Magira E, Monos D

Abstract excerpt

Sarcoidosis is a systemic granulomatosis of unknown etiology despite being described over 100 years ago. While both genetic predisposition and environmental exposures have been proposed as playing a role in this disease, there have not been any systematic investigations of gene-environmental interaction in this disease. In the ACCESS dataset, detailed environmental histories and high resolution HLA class II...

Topics

Adult
Alleles
Autoimmunity
DNA
Environmental Exposure
Female
Follow-Up Studies
Genes, MHC Class II
Genetic Predisposition to Disease
Humans
Male
Prospective Studies
Sarcoidosis

Source

Open in PubMed

Identifiers

PMID: 19382531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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