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Article

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.

Gut - 1 Feb 2011

Hayes C Nelson, Kobayashi Mariko, Akuta Norio, Suzuki Fumitaka, Kumada Hiromitsu, Abe Hiromi, Miki Daiki, Imamura Michio, Ochi Hidenori, Kamatani Naoyuki, Nakamura Yusuke, Chayama Kazuaki

Abstract excerpt

BACKGROUND AND AIMS: A number of recent studies have shown that human polymorphisms near the IL28B type III interferon (IFNλ) gene influence the response to peg-interferon plus ribavirin combination therapy for infection with chronic hepatitis C virus (HCV). Viral polymorphisms, including substitutions within the HCV core and NS5A proteins, have also been shown to influence treatment outcome, but it is not known...

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Identifiers

PMID: 21068134
DOI: 10.1136/gut.2010.223495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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