Article
Association between the leptin gene 2548G/A polymorphism, the plasma leptin and the metabolic syndrome with psoriasis.
Experimental dermatology - 1 Sept 2011
Abdel Hay Rania M, Rashed Laila A
Abstract excerpt
BACKGROUND: Psoriasis is a disorder with genetic and immunologic background. Leptin can regulate the T-helper response. OBJECTIVE: Our primary goal is to study the functional polymorphism (G-2548A) of the leptin (LEP) gene in the genetic predisposition of psoriasis, and our secondary goal is to examine factors affecting plasma leptin levels in psoriasis and to compare patients with and without metabolic syndrome...
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