Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial quality control and dynamics in Parkinson's disease.

Antioxidants & redox signaling - 1 May 2012

McCoy Melissa K, Cookson Mark R

Abstract excerpt

SIGNIFICANCE: Studies of sporadic cases, toxin models, and genetic causes of Parkinson's disease suggest that mitochondrial dysfunction may be an early feature of pathogenesis. RECENT ADVANCES: Compelling evidence of a causal relationship between mitochondrial function and disease was found with the identification of several genes for recessive parkinsonism, PINK1, DJ-1, and parkin. There is evidence that each of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Genes, Dominant
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Fusion

Share to Mitochondria

Share to Mitochondrial Membranes

Share to Mutation

Share to Parkinson Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 21568830
DOI: 10.1089/ars.2011.4019
PMCID: PMC3292751

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial quality control and dynamics in Parkinson's disease.PMID 21568830Read ↗

Mitochondrial Quality Control and Parkinson’s Disease: A Pathway UnfoldsSemantic proximity Read ↗

PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s diseaseSemantic proximity Read ↗

Mitochondrial quality control in neurodegenerative diseases.Semantic proximity Read ↗

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?Semantic proximity Read ↗

Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis.Semantic proximity Read ↗

Disruption of Mitochondrial Homeostasis: The Role of PINK1 in Parkinson’s DiseaseSemantic proximity Read ↗

Unravelling mitochondrial pathways to P arkinson's diseaseSemantic proximity Read ↗

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality ControlSemantic proximity Read ↗

PINK1/Parkin mitophagy and neurodegeneration—what do we really know in vivo?Semantic proximity Read ↗

Cell Death Pathways in Parkinson's Disease: Role of MitochondriaSemantic proximity Read ↗

Mitochondrial dysfunction in Parkinson’s diseaseSemantic proximity Read ↗

Balance is the challenge – The impact of mitochondrial dynamics in Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.