Article
T-cell immunoglobulin and mucin domain 3 genetic polymorphisms are associated with rheumatoid arthritis independent of a shared epitope status.
Human immunology - 1 Aug 2011
Song Yeong Wook, Im Churl Hyun, Park Jae Hee, Lee Yun Jong, Lee Eun Young, Lee Eun Bong, Park Kyungsook
Abstract excerpt
The aim of this study was to investigate T-cell immunoglobulin and mucin domain 3 (TIM3) genetic polymorphisms and rheumatoid arthritis (RA) according to the shared epitope (SE) status. Six single nucleotide polymorphisms (SNPs: rs11742259 [C/T], rs10515746 [C/A], rs35960726 [A/G], rs1036199 [A/C], rs4704846 [A/G], and [A/G]) in the TIM3 gene from 366 RA patients and 389 healthy controls were...
