Article
The exon 4 variations of Tim-1 gene are associated with rheumatoid arthritis in a Korean population.
Biochemical and biophysical research communications - 19 Mar 2004
Chae Soo-Cheon, Song Ju-Hee, Shim Seung-Cheol, Yoon Kyung-Sik, Chung Hun-Taeg
Abstract excerpt
The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of Tim family, TIM-1, is considered as a membrane protein that is associated with the development of Th2 biased immune responses and selectively expressed on Th2 cells. In the present study, we analyzed the association of genotype and allele frequencies between rheumatoid arthritis (RA)...
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