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Article

Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female population.

Journal of human genetics - 1 Jul 2011

Koga Minori, Kawasaki Aya, Ito Ikue, Furuya Takumi, Ohashi Jun, Kyogoku Chieko, Ito Satoshi, Hayashi Taichi, Matsumoto Isao, Kusaoi Makio, Takasaki Yoshinari, Hashimoto Hiroshi, Sumida Takayuki, Tsuchiya Naoyuki

Abstract excerpt

Although large-scale studies established many susceptibility genes to systemic lupus erythematosus (SLE), effect of each gene is not sufficiently large to be used alone to identify individuals with strong genetic predisposition. In this study, we analyzed the cumulative number of risk alleles at eight established susceptibility loci, HLA-DRB1, IRF5, STAT4, BLK, TNFAIP3, TNIP1, FCGR2B and TNFSF13, in 282 Japanese...

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Source

Identifiers

PMID: 21562514
DOI: 10.1038/jhg.2011.49

Genes

BLK
STAT4
TNFAIP3
TNFSF13
TNIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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