Article
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Neuromolecular medicine - 1 Jun 2011
Abramsson Alexandra, Landgren Sara, Zetterberg Madeleine, Seibt Palmer Mona, Minthon Lennart, Gustafson Deborah R, Skoog Ingmar, Blennow Kaj, Zetterberg Henrik
Abstract excerpt
Aggregation of amyloid-beta is one of the major characteristics in brains of patients with Alzheimer's disease (AD). Although several mechanisms behind the formation of such aggregates have been suggested the regulatory factors are still unknown. The present study aimed at investigating the association of lysyl oxidase-like 1 (LOXL1) polymorphisms with AD diagnosis and cerebrospinal fluid biomarkers (CSF) for the...
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