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Article

Signalogs: orthology-based identification of novel signaling pathway components in three metazoans.

PloS one - 3 May 2011

Korcsmáros Tamás, Szalay Máté S, Rovó Petra, Palotai Robin, Fazekas Dávid, Lenti Katalin, Farkas Illés J, Csermely Péter, Vellai Tibor

Abstract excerpt

BACKGROUND: Uncovering novel components of signal transduction pathways and their interactions within species is a central task in current biological research. Orthology alignment and functional genomics approaches allow the effective identification of signaling proteins by cross-species data integration. Recently, functional annotation of orthologs was transferred across organisms to predict novel roles for...

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PMID: 21559328
DOI: 10.1371/journal.pone.0019240
PMCID: PMC3086880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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