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OrthoList: A Compendium of C. elegans Genes with Human Orthologs

25 May 2011

Abstract excerpt

BACKGROUND: C. elegans is an important model for genetic studies relevant to human biology and disease. We sought to assess the orthology between C. elegans and human genes to understand better the relationship between their genomes and to generate a compelling list of candidates to streamline RNAi-based screens in this model. RESULTS: We performed a meta-analysis of results from four orthology prediction...

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PMID: 21647448
DOI: 10.1371/journal.pone.0020085

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