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Article

Identification and Classification of Acute Cardiac Rejection by Intragraft Transcriptional Profiling

10 May 2011

Abstract excerpt

BACKGROUND: Treatment of acute rejection (AR) in heart transplantation relies on histopathological grading of endomyocardial biopsies according to International Society for Heart and Lung Transplantation guidelines. Intragraft gene expression profiling may be a way to complement histological evaluation. METHODS AND RESULTS: Transcriptional profiling was performed on 26 endomyocardial biopsies, and expression...

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PMID: 21555702
DOI: 10.1161/circulationaha.109.913921

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