Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-based bio-signature patterns and cardiac allograft rejection.

Heart failure clinics - 1 Jan 2010

Mehra Mandeep R, Uber Patricia A, Benitez Roberto M

Abstract excerpt

Clinicians have long awaited an alternative to invasive endomyocardial biopsy for surveillance of cardiac transplant rejection. Transcriptional signals in peripheral blood mononuclear cells allow for the development of multigene-based panels that can inform on the presence or absence of immunologic quiescence. The informative genes represent several biologic pathways, including T-cell activation (PDCD1), T-cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Graft Rejection
Share to Heart Failure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Transplantation

Share to Multigene Family

Share to Myocardium

Share to Risk Assessment

Share to Transplantation Conditioning

Source

Identifiers

PMID: 19945064
DOI: 10.1016/j.hfc.2009.08.010

Genes

ITGA4
PDCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-based bio-signature patterns and cardiac allograft rejection.PMID 19945064Read ↗

Rejection Surveillance: Integrating Cell-Free DNA and Gene Expression Panels to Decrease Invasiveness in Routine Monitoring of Heart Transplant RecipientsSemantic proximity Read ↗

Comparing Plasma Donor–derived Cell-free DNA to Gene Expression in Endomyocardial Biopsies in the Trifecta-Heart StudySemantic proximity Read ↗

MicroRNA signatures in cardiac biopsies and detection of allograft rejectionSemantic proximity Read ↗

Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesisSemantic proximity Read ↗

RNA-sequencing of Human Kidney Allografts and Delineation of T-Cell Genes, Gene Sets, and Pathways Associated With Acute T Cell–mediated RejectionSemantic proximity Read ↗

Molecular Diagnosis of Heart Allograft Rejection Using Intra-Graft Targeted Gene Expression Profiling: the heart HistoMX systemSemantic proximity Read ↗

Transplantation: molecular phenotyping of T-cell-mediated rejection.Semantic proximity Read ↗

Utility of Plasma Cell-free Chromatin Immunoprecipitation to Detect Cardiac Allograft RejectionSemantic proximity Read ↗

Differentially Expressed Gene Transcripts Using RNA Sequencing from the Blood of Immunosuppressed Kidney Allograft RecipientsSemantic proximity Read ↗

Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart TransplantationSemantic proximity Read ↗

Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipientsSemantic proximity Read ↗

Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.