The sir locus of Escherichia coli: a gene involved in SOS-independent repair of mitomycin C-induced DNA damage.

doi:10.1016/0921-8777(90)90061-9

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Article

The sir locus of Escherichia coli: a gene involved in SOS-independent repair of mitomycin C-induced DNA damage.

Mutation research - 1 Mar 1990

Kumaresan K R, Jayaraman R

Abstract excerpt

A Mud1 (lac Apr) insertion has been isolated in a delta (lac)recA+ lexA3(Ind-)rpoB87 gyrA87 mutant of Escherichia coli resulting in a decrease in mitomycin C tolerance and an increase in post-mitomycin C DNA degradation. The mitomycin C sensitivity of the insertion mutant is not further increased...

Topics

Bacteriophage lambda
Chromosome Mapping
Cloning, Molecular
DNA Damage
DNA Repair
DNA Transposable Elements
Escherichia coli
Genes, Bacterial
Lac Operon
Mitomycin
Mitomycins
Mutation
SOS Response, Genetics

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