Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for involvement of UvrB in elicitation of 'SIR' phenotype by rpoB87-gyrA87 mutations in lexA3 mutant of Escherichia coli.

DNA repair - 1 Nov 2012

Shanmughapriya V, Munavar M Hussain

Abstract excerpt

An unconventional DNA repair termed SIR (SOS Independent Repair), specific to mitomycin C (MMC) damage elicited by a combination of specific Rif(R) (rpoB87) and Nal(R) (gyrA87) mutations in SOS un-inducible strains of Escherichia coli was reported by Kumaresan and Jayaraman (1988). We report here that the rpoB87 mutation defines a C(1565)→T(1565) transition changing S(522)→F(522) and gyrA87 defines a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Survival
Share to DNA-Directed RNA Polymerases
Share to DNA Gyrase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Helicases

Share to Escherichia coli Proteins

Share to Mitomycin

Share to Serine Endopeptidases

Share to Ultraviolet Rays

Source

Identifiers

PMID: 23058633
DOI: 10.1016/j.dnarep.2012.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for involvement of UvrB in elicitation of 'SIR' phenotype by rpoB87-gyrA87 mutations in lexA3 mutant of Escherichia coli.PMID 23058633Read ↗

Selective alleviation of Mitomycin C sensitivity in lexA3 strains of Escherichia coli demands allele specificity of rif-nal mutations: a pivotal role for rpoB87-gyrA87 mutations.Semantic proximity Read ↗

The sir locus of Escherichia coli: a gene involved in SOS-independent repair of mitomycin C-induced DNA damage.Semantic proximity Read ↗

Enhanced sensitivity of Escherichia coli uvrB mutants to mitomycin C points to a UV-C distinct repair for DNA adducts.Semantic proximity Read ↗

Transcriptional coupling and repair of 8-OxoG activate a RecA-dependent checkpoint that controls the onset of sporulation in Bacillus subtilis.Semantic proximity Read ↗

Structural and functional characterization of the Bacillus megaterium uvrBA locus and generation of UV-sensitive mutants.Semantic proximity Read ↗

Mismatch-induced lethality due to a defect in Escherichia coli RecQ helicase in exonuclease-deficient background: Dependence on MutS and UvrD functions.Semantic proximity Read ↗

The Regulation of LexA on UV-Induced SOS Response in Myxococcus xanthus Based on Transcriptome Analysis.Semantic proximity Read ↗

The role of mutation frequency decline and SOS repair systems in methyl methanesulfonate mutagenesis.Semantic proximity Read ↗

The SOS system.Semantic proximity Read ↗

DNA mutagenesis and repair in UV-irradiated E. coli K-12 under condition of mutation frequency decline.Semantic proximity Read ↗

lon incompatibility associated with mutations causing SOS induction: null uvrD alleles induce an SOS response in Escherichia coli.Semantic proximity Read ↗

Histone-like protein HU is required for recA gene-dependent DNA repair and SOS induction pathways in UV-irradiated Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.