Article
Rapid molecular evolution of wild type 3 poliovirus during infection in individual hosts.
The Journal of general virology - 1 Feb 1990
Kinnunen L, Huovilainen A, Pöyry T, Hovi T
Abstract excerpt
A panel of nine neutralizing monoclonal antibodies was used to analyse the antigenic properties of 188 plaque-purified type 3 poliovirus strains from 17 faecal specimens, derived from eight people during a 2 month observation period. Most poliovirus specimens consisted of a mixture of antigenical...
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antigenic Variation
- Antigens, Viral
- Base Sequence
- Disease Outbreaks
- Feces
- Finland
- Humans
- Molecular Sequence Data
- Mutation
- Neutralization Tests
- Poliomyelitis
- Poliovirus
- RNA, Viral