Article
Rapid molecular evolution of wild type 3 poliovirus during infection in individual hosts.
The Journal of general virology - 1 Feb 1990
Kinnunen L, Huovilainen A, Pöyry T, Hovi T
Abstract excerpt
A panel of nine neutralizing monoclonal antibodies was used to analyse the antigenic properties of 188 plaque-purified type 3 poliovirus strains from 17 faecal specimens, derived from eight people during a 2 month observation period. Most poliovirus specimens consisted of a mixture of antigenically distinct variants and the composition of the mixture was found to change between sequential specimens in many...
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