Article
The Drosophila Na,K-ATPase alpha-subunit gene: gene structure, promoter function and analysis of a cold-sensitive recessive-lethal mutation.
Genes and function - 1 Apr 1997
Feng Y, Huynh L, Takeyasu K, Fambrough D M
Abstract excerpt
The Drosophila Na,K-ATPase (or sodium pump) alpha-subunit gene was found to contain 10 exons and span approx. 25 kb. Two nearly adjacent transcriptional initiation sites were identified, and the 2085-nucleotide sequence upstream of the first transcriptional start was analysed for promoter activit...
Topics
- Adaptation, Physiological
- Animals
- Base Sequence
- Cell Line
- DNA
- DNA Footprinting
- DNA Transposable Elements
- Drosophila
- Exons
- Genes, Lethal
- Genes, Recessive
- Heterozygote
- Homozygote
- Introns
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein Binding