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Article

CNTF Induces Regeneration of Cone Outer Segments in a Rat Model of Retinal Degeneration

2 Mar 2010

Abstract excerpt

BACKGROUND: Cone photoreceptors are responsible for color and central vision. In the late stage of retinitis pigmentosa and in geographic atrophy associated with age-related macular degeneration, cone degeneration eventually causes loss of central vision. In the present work, we investigated cone degeneration secondary to rod loss in the S334ter-3 transgenic rats carrying the rhodopsin mutation S334ter....

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PMID: 20209167
DOI: 10.1371/journal.pone.0009495

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