Article
Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies.
Respiratory research - 28 Mar 2013
Clarke Luka A, Sousa Lisete, Barreto Celeste, Amaral Margarida D
Abstract excerpt
BACKGROUND: Microarray studies related to cystic fibrosis (CF) airway gene expression have gone some way in clarifying the complex molecular background of CF lung diseases, but have made little progress in defining a robust "molecular signature" associated with mutant CFTR expression. Disparate methodological and statistical analyses complicate comparisons between independent studies of the CF transcriptome, and...
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