Article
Biochemical and molecular analysis of spontaneous and induced mutations at the mouse Mod-1 locus.
Mutation research - 1 Feb 1990
Cobb R R, Burkhart J G, Dubins J S, Barnett L B, Lewis S E
Abstract excerpt
We have analyzed five Mod-1 (malic enzyme) mutants at the molecular and biochemical level. Four of these mutants, three electrophoretic variants and one null mutant, were induced by ethylnitrosourea (ENU). Another null mutant was the result of a spontaneous mutation. All of these mutations were heritable in a Mendelian fashion and viable in the homozygous condition. Restriction endonuclease and Southern blot...
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