Article
Biochemical genetics of methylglyoxal dehydrogenases in the laboratory rat (Rattus norvegicus).
Biochemical genetics - 1 Jun 1994
Bender K, Seibert R T, Wienker T F, Kren V, Pravenec M, Bissbort S
Abstract excerpt
A genetic locus controlling the electrophoretic mobility of a methylglyoxal dehydrogenase (EC 1.2.1.23) in the rat is described. The locus, designated Mgd1, is expressed in liver and kidney. Inbred rat strains have fixed either allele Mgd1a or allele Mgd1b. Codominant expression is observed in heterozygotes, providing evidence for a tetrameric enzyme structure. Backcross progenies showed the expected 1:1...
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