Pigment epithelium-derived factor gene polymorphisms in exudative age-related degeneration in a chinese cohort.

doi:10.3109/02713683.2010.524343

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Pigment epithelium-derived factor gene polymorphisms in exudative age-related degeneration in a chinese cohort.

Current eye research - 1 Jan 2011

Qu Yi, Zhang Xiaoyan, Dai Hong, Zhou Fang, Xu Xiaoyi, Zhang Xiao, Bi Hongsheng, Pan Xuemei, Wang Hongge, Jiang Hua, Yin Ningning, Dang Guangfu

Abstract excerpt

PURPOSE: To investigate polymorphisms in the pigment epithelium-derived factor (PEDF) gene in a Chinese cohort with exudative age-related macular degeneration (AMD). METHODS: Two common single nucleotide polymorphisms (SNPs), Met72Thr (rs1136287) and -5736T>C (rs12150053), were genotyped, and four tagSNPs (tSNPs) were detected statistically in the PEDF gene of 168 exudative AMD patients and 230 age- and...

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PMID: 21174599
DOI: 10.3109/02713683.2010.524343

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