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Article

Host genetics.

Current opinion in HIV and AIDS - 1 Nov 2011

Macías Juan, Vispo Eugenia, Pineda Juan A, Soriano Vicente

Abstract excerpt

PURPOSE OF REVIEW: To update the information on genetic markers influencing the outcome of hepatitis C virus (HCV) infection. RECENT FINDINGS: Single-nucleotide polymorphisms (SNPs) in the region of the IL28B gene on chromosome 19, coding for the interferon (IFN)-λ3, are involved in HCV spontaneous and treatment-induced clearance, and may have an influence on liver fibrosis and inflammation in chronic carriers....

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Identifiers

PMID: 21918436
DOI: 10.1097/COH.0b013e32834bca2d

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