Article
Dual genotype in cutaneous T-cell lymphomas and pseudolymphomas.
Human genetics - 1 Jan 1990
Bignon Y J, Souteyrand P, Roger H, Bernard D, Dastugue B, Ramos F, d'Incan M, Chollet P, Plagne R
Abstract excerpt
Genomic DNA digests of skin biopsies from 20 patients with cutaneous T-cell lymphomas and pseudolymphomas were studied by hybridization, using probes for the constant region of the T-cell receptor beta chain and the joining region of the immunoglobin heavy chain gene. Skin biopsies from all 20 patients contained a monoclonal T-cell population. In addition, DNA from 5 patients contained an immunoglobulin gene...
Topics
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genotype
- Humans
- Immunoglobulin Joining Region
- Lymphoma
- Skin Neoplasms
- T-Lymphocytes
