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Article

Unrelated Hematopoietic Stem Cell Donor Matching Probability and Search Algorithm

13 Nov 2012

Abstract excerpt

In transplantation of hematopoietic stem cells (HSCs) from unrelated donors a high HLA compatibility level decreases the risk of acute graft-versus-host disease and mortality. The diversity of the HLA system at the allelic and haplotypic level and the heterogeneity of HLA typing data of the registered donors render the search process a complex task. This paper summarizes our experience with a search algorithm...

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PMID: 23198148
DOI: 10.1155/2012/695018

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