Article
Race/ethnicity affects the probability of finding an HLA-A, -B, -C and -DRB1 allele-matched unrelated donor and likelihood of subsequent transplant utilization.
Bone marrow transplantation - 1 Mar 2013
Pidala J, Kim J, Schell M, Lee S J, Hillgruber R, Nye V, Ayala E, Alsina M, Betts B, Bookout R, Fernandez H F, Field T, Locke F L, Nishihori T, Ochoa J L, Perez L, Perkins J, Shapiro J, Tate C, Tomblyn M, Anasetti C
Abstract excerpt
Factors relevant to finding a suitable unrelated donor and barriers to effective transplant utilization are incompletely understood. Among a consecutive series of unrelated searches (n=531), an 8/8 HLA-A, -B, -C and -DRB1-matched unrelated donor was available for 289 (54%) patients, 7/8 for 159 (30%) and no donor for 83 (16%). Patients of Caucasian race (P<0.0001) were more likely to find a donor. Younger age...
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